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There are easy things that patients can do to help, says FitzGerald such as beginning with a lower dose, eating smaller meals, and staying hydrated

"The most important one is just the weight loss and therefore less stress on the spine

Have lost 40 pounds (!) in two months, eat anything and everything just way less and no desire to snack between

Originally developed by Chugai Pharmaceuticals under the code OWL-833 and licensed by Lilly in 2018, orforglipron represents an exciting departure from traditional peptide-based therapies

Acknowledgements The work was supported by the Swiss National Science Foundation grants 31003A_175658 to V.L.K