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What This Means for Women in Midlife If you're considering a GLP-1 medication for weight management, the question isn't just "which medication?" it's "what else is going on hormonally?" For women in perimenopause or postmenopause, addressing estrogen deficiency may: Enhance the weight loss response to GLP-1 medications [1] Improve the metabolic benefits including better insulin sensitivity and reduced visceral fat [7, 8] Address symptoms like sleep disruption, hot flashes, and mood changes that can undermine weight loss efforts [10] Support long-term cardiovascular health during a period of accelerated risk [9] This is why a comprehensive approach one that evaluates both your metabolic health and your hormonal status matters so much more than choosing a single medication in isolation
10.1038/75068 6 BojarskaJ
The initial collaboration between the Trapp, de Lartigue and Langhans labs which generated this work was made possible thanks to a UCL Global Engagement Fund award to DB, and a UCL Neuroscience ZNZ Collaboration award to ST and WL
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Applied and Environmental Microbiology, 72 , 17291738
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