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Isolation and culture of embryonic cortical NSCs NSCs were harvested from the cerebral cortex of Wistar rat embryos at E13.5 as described previously with slight modification [40]

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Candidate compounds or drugs that could significantly reverse the disease-related signatures of gene expression were further validated in vitro , showing that this computational method is a viable approach for identifying novel therapeutics

Targeting the translational apparatus to improve leukemia therapy: Roles of the PI3K/PTEN/Akt/mTOR pathway