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It was not approved for treatment of dementia or Alzheimers Disease
It is about recalibrating nutrient sensing, reducing toxic fat depots, and damping the signals of metabolic stress that ripple through every organ system
Patel SK et al
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GPX7 can transmit oxidative stress signals by forming disulfide bonds between its catalytic sites Cys57 and Cys86 residues, and this oxidized form of GPX7 can bind to each other with GRP78 and form covalent bond intermediates between Cys86 of GPX7 and Cys41/Cys420 of GRP78 (Nguyen et al., 2011
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