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Abbreviations 2SC: 2-succinyl-cysteine aKG: Alpha-ketoglutarate ARA+EPA: Arachidonic acid and eicosapentaenoic acid ATP: Adenosine triphosphate ATS: American Thoracic Society AUC: Area under the receiver operating characteristic curve BC-CCI: British Columbia Cognitive Complaints Inventory bp: Base pair C: Cholesterol CK: Creatine kinase CMC: Carboxymethyl-cysteine CML: Carboxymethyl-lysine CPCA: Consensus principal component analysis DHA: Docosahexaenoic acid D LCO : Lung diffusing capacity for carbon monoxide DLN: Dry low nitroxides EC: Esterified cholesterol edf: Effective degrees of freedom FACIT: Functional Assessment of Chronic Illness Therapy FC: Free cholesterol GAM: Generalized additive modeling Glyc: Glycoprotein GC/MS: Gas chromatographymass spectrometry H-NMR: Proton nuclear magnetic resonance spectroscopy H/W: Height to bandwidth HADS: Hospital Anxiety and Depression Scale HACA: Aminocaproic acid HAVA: Aminovaleric acid ICU: Intensive care unit IDL: Intermediate-density lipoprotein IS: Internal standard LA: Linoleic acid LDL: Low-density lipoprotein LMWM: Low molecular weight metabolites LOESS: Locally Weighted Scatter-plot Smoother LOOCV: Leave-one-out cross validation LPC: Lysophosphatidylcholine MDAL: Malondialdehyde-lysine ML: Machine learning mMRC: Modified Medical Research Council MSD: Mass selective detector NIST: National Institute of Standards and Technology NRL: L-norleucine OXPHOS: Oxidative phosphorylation P: Particle number PASC: Post-acute sequelae of COVID-19 PBS: Phosphate buffer solution PCA: Principal component analysis PL: Glycerophospholipids, except LPC PLS-DA: Partial least square discriminant analysis PUFA: Polyunsaturated fatty acids RF: Random forest ROC: Receiver operating characteristic ROS: Reactive oxygen species SF-12: Mental and physical scores from the 12-Item Short Form Survey SIM: Selecting ion monitoring TCA: Tricarboxylic acid TFAME: N,O-trifluoroacetyl methyl ester TG: Triglycerides VLDL: Very low density lipoprotein W3: Omega-3 fatty acids w6+w7: Omega-6 and omega-7 fatty acids W9: Omega-9 fatty acids WHO: World Health Organization Z: Diameter References Soriano JB, Murthy S, Marshall JC, Relan P, Diaz J V

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