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Although ACA exhibited no noticeable impact on early rat hepatocarcinogenesis in vivo, it suppressed the growth of HepG2 and MH1C1 cells [128]

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First, the sample size was small and not based on a statistical power calculation

The results showed that the treatment with Ru(II)-OH reduced the tumor volume by 35%, the treatment with NP2 by 66%, and the treatment with NP4 by 91% (Fig