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GLP-1 receptor agonists versus metformin in PCOS: A systematic review and meta-analysis

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Consider treatment response and tolerability when selecting the maintenance dosage Cardiovascular risk reduction maintenance dose: Either 2.4 mg (recommended) or 1.7 mg once weekly, based on patient response and tolerance

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45,46 These results were confirmed by a pooled analysis that demonstrated that the improvement in quality of life and functional capacity may be primarily related to weight loss, and that there were significant declines in HF hospitalisations or urgent visits (8 [1%] versus 30 [5%] patients in the semaglutide and placebo groups, respectively

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