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[70] found in vivo and in vitro studies that GLP-1 and its analog exendin-4 were able to induce an increase in ABCA1 mRNA, increase the expression of apo AI mRNA and promoter, thereby increasing apo AI secretion, indicating that GLP-1 in hepatocytes may mediate the outflow of intracellular cholesterol to apo AI through the ABCA1 pathway

Profiles of the Common GLP-1 Receptor Agonists Note: All may cause significant/severe GI symptoms including nausea, vomiting, retching, gastroparesis, abdominal bloating, and pain

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