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Next, the ability of these cells to mutate Dnd1 in vivo was tested by injecting CAG-C9-3 cells infected with a lentivirus carrying Dnd1 sgRNA1 into oocytes to produce semi-cloned embryos (Supplementary information, Fig

ISCs are involved in electron transport, substrate binding, enzymatic catalysis and play critical roles in maintaining genomic stability since several DNA polymerases and helicases require interaction with ISCs for proper functioning