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The trigger is the combination of rapid weight loss and caloric restriction: when appetite suppression is working well, patients are eating significantly less, and if protein and micronutrient intake fall below what the body needs, hair follicles are among the first structures deprioritized
The bacterial growth in the vial is prevented by the preservative
Scand J Haematol 1982;29:311-318 Pezacka E, Green R, Jacobsen DW
The pricing reflects its status as a research compound with limited demand and specialized sourcing requirements
One possible explanation is that low serum vitamin B12 levels would trap folate as 5-methyltetrahydrofolate, prevent the generation of methionine from homocysteine, and therefore reduce protein synthesis and lean tissue deposition
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