Given the broad age range of our cohort (0.214.1 years), we implemented NFM, a theory-based size descriptor that divides WT into FFM and fat mass (Gonzalez-Sales et al., 2022), to quantify the effect of body size and composition on busulfan PK, consistent with the study by McCune et al
A larger Novo Nordisk-funded trial found that patients in earlier stages taking semaglutide were more likely than those on a placebo to see their NASH resolved, but not significantly more likely to see their scarring improve
Mosenzon O, Aroda VR, Christiansen E, Harris SB, Boje Pedersen K, Tarp-Johansen MJ, et al
These studies established its safety profile, optimal dosing, and effectiveness for both diabetes management and weight loss
Studies say Ozempic is mostly safe, but it can cause stomach problems