510% weight loss is considered clinically meaningful with pharmacotherapy
Additionally, evening dosing may be more convenient for individuals with busy morning schedules or those who prefer to administer injections in the privacy of their home after work
What the clinical data has reported: Phase 2 trials of Retatrutide (Jastreboff et al., NEJM 2023, and follow-ups) reported: - Dose-dependent body weight reduction across 24- and 48-week dosing intervals - Reductions in liver fat content measured by MRI-proton density fat fraction (MRI-PDFF) in populations with metabolic dysfunction-associated steatotic liver disease (MASLD) - Glycaemic marker improvement (HbA1c, fasting glucose) in type 2 diabetes cohorts - Dose-related gastrointestinal adverse effects consistent with the GLP-1/GIP class nausea, vomiting, diarrhoea Important: these are clinical trial findings in regulated patient populations
Use only as a dietary supplement
Our experience led to a proof-of-concept study in the insulin-secreting pancreatic -cell line, MIN-6, and the GLP-1-secreting intestinal L-cell line, GLUTag