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Among these, tirzepatide, a long-acting dual GLP-1R/GIPR agonist approved for diabetes and obesity, shows enhanced therapeutic outcomes on cardiometabolic diseases compared to selective GLP-1R agonists (20, 33, 34)
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What is the distinct NAD + metabolome in each tissue
Only tirzepatide was associated with a greater proportion of patients achieving at least 25% TBWL reduction (odds ratio [95% confidence interval]: 33.8 [18.461.9], P 10%)
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