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Aging is accompanied by deteriorating proteostasis and altered modification landscapes, which compromise the reversible and dynamic property of LLPS, triggering the formation of aberrant, solid-like aggregates that exacerbate neuronal dysfunction and neurodegeneration

In a phase 2b randomized placebo-controlled trial, semaglutide 2.4 mg OW significantly reduced abdominal visceral, subcutaneous, and total body fat in people with HIV-associated lipohypertrophy without diabetes [152] (Figs

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Yes, GLP-1 medications and testosterone replacement have no direct contraindication and are frequently used together