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GLP-1 medications may be contraindicated if you have or have a history of: personal and family history of papillary and follicular thyroid cancers (given that there may be an increased risk based on animal studies) chronic nausea, vomiting or gastroparesis (as GLP-1s slow down gastric emptying and may worsen GI symptoms) pancreatitis (GLP-1s may increase the risk of pancreatitis or inflammation of the pancreas) children under 12 years old currently pregnant or breastfeeding eating disorders allergy or hypersensitivity to the medication weight cycling (losing and gaining weight back) without needing to lose weight for health reasons Always consult a healthcare professional before starting GLP-1 medications to ensure they align with your health needs and treatment plan

Sterile Water for Injection, USP is specified as containing no bacteriostat, antimicrobial agent or added buffer, so nothing suppresses microbial growth once the seal is broken, and it is treated as a single-use article

A complete guide to insurance coverage Key highlights Zepbound is an FDA-approved subcutaneous injection prescribed to patients with obesity and overweight with a weight-related medical condition

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Diabetes Care 47 (2), 280284 (2024)