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The SELECT trial (N=17,604) added a cardiovascular dimension: semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% versus placebo in adults with overweight or obesity and established cardiovascular disease, over a mean follow-up of 34.2 months [6]

Elimination of the excess fat has repeatedly been shown to improve these variables and reduce risk of cardiovascular events, so why wouldnt we expect that semaglutide a medication with well-established efficacy in promoting weight loss would do the same

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The impact of GLP-1 receptor agonists (GLP-1 RAs) on mental health: a systematic review

Thermodynamic and kinetic characterization of Co C bond homolysis catalyzed by coenzyme B12-dependent methyl malonyl-CoA mutase