For patients whose primary goal is weight management alongside diabetes control, NICE guidance (NG28) supports considering SGLT2 inhibitors, which are generally weight-neutral or beneficial
Similarly, the use of Tesofensine also showcases an increase in the other two monoamine neurotransmitters, noradrenaline and serotonin
However, SOD does not have a widespread usage in human clinical medicine
For now, the most important thing to keep in mind is that retatrutide is still evolving
SUSTAIN 9: Ozempic injection as an add-on to SGLT-2i MET/SU 6 Study design: 30-week, multinational, randomized, double-blind, parallel-group, placebo-controlled trial evaluating the efficacy and safety of adding Ozempic injection 1 mg to SGLT-2i metformin/sulfonylurea vs SGLT-2i + placebo metformin/sulfonylurea