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This suppression contributes to the accumulation of toxic protein aggregates and aggravates immune imbalance (Lehrman et al., 2018
These two powerhouses create mutually beneficial effects that amplify their individual benefits
Interestingly, although mammalian GR somewhat resembles the TrxR domain of SmTGR, the GR domain of SmTGR has the fold of Trx and is appended to the N-terminus of the TrxR core of SmTGR, containing the C28-C31 pair (Figure 1)
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