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On the one hand, the renin-angiotensin system (RAS) induces inflammation by stimulating the release of inflammatory cytokines through angiotensin II, increasing the production of ROS [139]
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Initial changes may appear within 4-8 weeks, with optimal results visible after completing the full course of treatment
The incidence of this behaviour is increasing ..This appears to be due to a cost saving exercise and largely happens without any prior consultation with individual patients to discuss their needs
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