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The tryptophan residue is at risk of oxidative degradation, forming impurities like kynurenine under photodegradation conditions
Research Applications Dual Incretin Pharmacology GIP+GLP-1R co-agonism, receptor interaction, GIPR adipose signalling T2D Research SURPASS program up to 2.58% HbA1c reduction vs placebo Obesity Models SURMOUNT-1: 22.5% weight reduction (15mg, 72 weeks) NASH/Liver SYNERGY-NASH: 62.4% NASH resolution at 10mg vs Semaglutide Head-to-head SURMOUNT-5 reference compound Quick Specs Certificate of Analysis (COA) Frequently Asked Questions How do I reconstitute Tirzepatide

* Adds Shot Notes to collapsed view on Shots screen for easy browsing of notes * Charts on Shots screen now show a minimum of 5 days * Now always shows 'Jump to today' button on Estimated Medication Level chart * Calendar selected day sheet now has a static position, instead of inline, making it easier to select other dates on the calendar version 2.7.2 posted on 2026-02-15 Changes in this update: * Fixes crash on Export PDF Summary on iOS 26.3 * Adds toggle for importing local backups * Adds announcement for new icon, coming soon version 2.4.4 posted on 2025-10-23 Oct 23, 2025 Version 2.4.4 We're preparing for some great performance improvements in our next release