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Binding specificity and mechanistic insight into glutaredoxin-catalyzed protein disulfide reduction

Rare but serious adverse effects on the pancreas and gallbladder have been reported

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Neuron 14:11051116 Mattiazzi M, DAurelio M, Gajewski CD et al (2002) Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice

It pairs NAD+ pathway activation with glutathione-powered antioxidant protection , targeting two biological foundations of aging: energy and redox balance