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It is handed between proteins in a thermodynamic hierarchy, and the relevant partners named in the GHK literature include serum albumin, which has a dedicated high-affinity N-terminal site, ceruloplasmin as the dominant circulating copper protein, metallothioneins as high-capacity intracellular sinks, and cuproenzymes that require the metal to function

The underlying peptide is the same

These compounds are extensively present in various commonly used Chinese herbal medicines, such as Scutellaria baicalensis Georgi [Lamiaceae, Scutellariae Radix], Angelica sinensis (Oliv.) Diels [Umbelliferae, Angelicae Sinensis Radix], Lycium barbarum L