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FOXO4-DRI eliminated fibroblasts in G0/G1 phase cell cycle arrest and selectively induced senescent keloid cells apoptosis in an in vitro model of fibroblasts and organ culture In the serum limitation-induced senescent fibroblast model, more SA--gal-positive cells were observed in keloid fibroblasts compared with that in normal skin fibroblasts (Fig

Combining them in one vial lets researchers examine both pathways in a single experimental system

Famenini, S., & Goh, C

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BPC-157 is typically injected for internal healing, while GHK-Cu can be used both topically (skin) and injected (systemic)