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doi:10.1210/endo.142.12.8522 Heffernan MA, Thorburn AW, Fam B, et al
[21] Within cells, cyanocobalamin is converted to methylcobalamin and 5- deoxyadenosylcobalamin, coenzymes that participate respectively in homocysteine remethylation to methionine and in the isomerization of methylmalonyl-CoA to succinyl CoA, reactions essential for DNA synthesis, erythropoiesis, and myelin maintenance
It contains a small amount of cyanide which the body must detoxify, is shorter-acting and is not recommended by NICE for clinical use
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This sustained absorption profile makes shots well suited for routine maintenance and diagnosed deficiencies like pernicious anemia, particularly when only B12 replenishment is needed
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