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MC1R receptor density recovers approximately 812% weekly following agonist withdrawal, reaching 8590% baseline by week 4 and 95100% by week 68

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Appl Microbiol Biotechnol 98(17):75497557 Seo M et al (2013) Clostridium butyricum MIYAIRI 588 improves high-fat diet-induced non-alcoholic fatty liver disease in rats