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Neurological benefit : The brain's high oxygen consumption and limited antioxidant defenses make hydrogen's ability to cross the blood-brain barrier especially valuable for neurological protection
Neuroscience & Biobehavioral Reviews, 114, 134-155
In Vitro Amitriptyline hydrochloride (0.5-10 M, 3.5-16.5 h) effectively resists cell apotosis (EC 50 = 50 nM) in T17 cells and shows no protective effect on the SN56 cells, and in primary rat hippocampal neurons stimulated by glutamate and subjected to oxygen-glucose deprivation (OGD), the neuronal apoptosis is significantly reduced [3]
somatostatin receptor targeting in malignant insulinomas
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