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| Take home message A recent announcement from Novo Nordisk, the pharmaceutical company that manufactures Wegovy (semaglutide 2.4mg), declared that preliminary results from their latest trial had shown a 20% reduction in the number of major cardiovascular events (MACE), like a heart attack or stroke, compared to placebo
Our approach is simple and straightforward
Glucagon receptor activation increases energy expenditure directly, potentially offsetting some of the adaptive thermogenesis that drives stalls on other GLP-1 medications
Tirzepatide is different from semaglutide because it also mimics the GIP hormone, so it not only affects stomach emptying and appetite, but also affects how fat is deposited in the body
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