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While extended vitamin D supplementation (6 months) in DRE patients correlates with reduced SF, caution is warranted: excessive maternal vitamin D intake during gestation elevates neonatal 25-hydroxyvitamin D3 levels, which may correlate with increased risk of childhood epilepsy (particularly cases initially diagnosed between ages 14 years)

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This approach has no comparative trial data but is mechanistically defensible given GHK-Cu's dose-dependent effects on fibroblast activity observed in vitro