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Higher doses reached that plateau later in the trial. In a 112-week step-down trial, participants maintained 21.9% loss on the top dose, 16.6% after stepping down to 5 mg, and 9.9% on placebo
Patients with tendinopathy often describe the first noticeable shift as less sharp pain when loading the tendon
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Exposure to heat, moisture, or light accelerates degradation
K.O'GradyK.CaulfieldJ
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