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Furthermore, leptin receptor-deficient mice, a mouse model of obesity and diabetes, and people with endogenous glucagon deficiency (pancreatectomised individuals) treated with glucagon antisense oligonucleotide have increased hepatic fat [52, 53]

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Incretin therapies: highlighting common features and differences in the modes of action of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors

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