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Not all potential applications have been validated in human clinical trials
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Overview of current and emerging GLP-1 receptor agonists
47 Visceral fat accumulation in patients with obesity causes a number of changes (oxidative stress, activation of the RAAS and gut dysbiosis), resulting in insulin resistance, increased vascular stiffness, T2D, dyslipidaemia, hypertension, coronary atherosclerosis and, ultimately, HFpEF
2015 Nov 5;6:264
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