"When I treat patients in the diabetes clinic, I see a huge variation in response to these GLP-1-based medications and it is difficult to predict this response clinically," says endocrinologist Mahesh Umapathysivam, from Adelaide University in Australia
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The medication makes caloric surplus extremely difficult to achieve
In addition, labile iron pools can catalyze lipid radical propagation through Fenton-type reactions, further amplifying membrane lipid peroxidation [71, 72]