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The MAPK/ERK axis runs in parallel

Leukocytes, inflammatory cells, offer valuable insights into the detection of inflammatory diseases and the characterization of inflammation regarding its severity and type (Tvedten and Raskin 2012)

A cooperative role of NRF2 and C/EBP (a transcription factor of the CCAAT/enhancer binding protein family) was described in generating tumor-specific enhancers that promote tumor initiation via NOTCH3 activation (Okazaki et al, 2020)

Stem cell niches may reactivate in cleared tissue Months 1-6+: Gradual tissue remodeling and functional recovery in organs where senescent cell burden was reduced This cascade explains why FOXO4-DRI doesn't produce immediate, obvious effects

doi: 10.3389/fpsyt.2022.977538 212 LiZQingYCuiGLiMLiuTZengYet al