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Therefore, recent research by cosmetic companies and research institutions has been focusing on the development of novel whitening agents that selectively suppress the activity of tyrosinase (TYR) to reduce hyperpigmentation whilst avoiding cytotoxicity to normal, healthy melanocytes

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The scheme accepts reports from healthcare professionals, patients, and carers, recognising that patient-reported outcomes provide valuable real-world safety data

(16) Abo-Elenin et al

Studies were screened for relevance to the mechanisms of action, clinical applications, chemical formulations, or adverse effects of self-tanning molecules