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Serious but Rare: Pancreatitis, cholelithiasis, renal impairment (monitor hydration)
observed reversal of diastolic ventricular dysfunction in a rat model due DPP4 inhibition, via local actions on angiogenesis and inotropic effects [76]
Fortunately for them, unfortunately for the research committee, their skulls were intact so they couldn't measure directly in the brain
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