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A GP surgerys refusal to administer an injection a day early often stems from a rigid interpretation of the standard maintenance schedule, rather than a flexible approach that accounts for individual patient needs and symptoms

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This could lead to a form of jaundice-induced brain damage called kernicterus, a rare disorder in which bilirubin is deposited in the brain, leading to vision and hearing loss that can be permanent.56 Likewise, children under 18 should not take berberine supplements

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To date, the trial has enrolled 94 participants, with 54 in the T2DM group and 40 in the obesity group