Anaemia A deficiency in red blood cells can cause anaemia, leading to fatigue, weakness, and shortness of breath
Preclinical and preliminary clinical evidence of semaglutides potential beneficial effects on various substance use disorders led us to evaluate if it pertained to CUD
Other short-term problems can include mild headaches and abdominal pain
Maintenance doses are typically 1 mg every 2-3 months for life High-dose oral therapy (1000-2000 micrograms daily) may be effective in selected patients with pernicious anaemia under clinical supervision, as passive diffusion can compensate for absent intrinsic factor, though this is not routine first-line treatment in the UK The water-soluble nature of B12 means that high-dose supplementation carries minimal risk of toxicity , making it a safe option for individuals with confirmed or suspected deficiency
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