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It should be noted that there are many known risks associated with vitamin B12 deficiency during pregnancy

It can also raise inflammation and lower a protein involved in controlling the amount of estrogen and testosterone actively present in the body

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Mechanisms underlying muscle healing enhancement include increased angiogenesis supporting tissue oxygenation and nutrient delivery, enhanced satellite cell activation for muscle regeneration, and reduced inflammatory damage during acute injury phases

The first-line simple advice to ensure adequate fluid and fibre intake should be reiterated, and a fibre supplement given if patients are reluctant or unable to increase dietary fibre