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An early publication in the Annals of the New York Academy of Sciences documenting the original discovery of telomere shortening as a primary mechanism of cellular senescence and its relevance to human aging biology provides the foundational framework for understanding why telomerase-activating compounds attract longevity research attention

For people on vegetarian or vegan diets, up to 90% have a vitamin B12 deficiency: even those who take extra vitamins

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First, acute and chronic EtOH administration induce overproduction of ROS, RNS and other free radicals, observations made in cell cultures, experimental animals and human subjects