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Furthermore, epigenetic age acceleration (EAA), an epigenetic biomarker of aging, has been linked to indoor air pollution from coal combustion and associated pulmonary arterial hypertension, particularly 5-methylcytosine, which correlates with the mortality biomarker Grim Age EAA [158]
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The 2-month-old S8/ Gss / male mice exhibited normal fertility, due to a compensatory increase in GPX4, which prevented the accumulation of ROS
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