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While the body does produce natural GLP-1, this endogenous hormone is rapidly broken down by the enzyme dipeptidyl peptidase-4 (DPP-4) within minutes of secretion, making it unsuitable as a therapeutic agent without pharmaceutical modification

Effect on oxidative stress In an animal study conducted by Wang et al., L-carnitine administration led to a significant elevation in Superoxide Dismutase (SOD) and Glutathione Peroxidase (GSH-Px) levels in both serum and cardiac tissue, accompanied by a marked reduction in malondialdehyde (MDA) levels

Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration

CagriSema produces 22 to 23%

CagriSema is a combination of cagrilintide (2.4mg) and semaglutide (2.4mg) in a single weekly injection