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BMC Endocr Disord

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The SURMOUNT-1 data shows diminishing returns at higher doses: 5mg produced 15% weight loss, 10mg produced 19.5%, and 15mg produced 20.9%

LFQ proteomic analysis provides revealing insight into the putative mechanisms facilitating this observation

However, side effects of GLP-1 RAs, particularly those affecting the gastrointestinal system, may limit their use in patients with IBD