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In another RDP clinical study, 156 osteoarthritis patients, took 100 mg Pycnogenol day or placebo for three months (42)

Retatrutide Retatrutide is an investigational weight-loss medication not yet approved by the FDA

Peer review Peer review information Nature Communications thanks Kathrin Ulrich and John Mieyal for their contribution to the peer review of this work

doi: 10.1080/08998280.2025.2456441

Clinically, EOAD progresses rapidly and may present with atypical symptoms such as visuospatial dysfunction, apraxia, or language impairment (Marshe et al., 2019