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At the same time, the production of reactive substances or impaired activity of the antioxidant system underlies various forms of epilepsy, thus increasing the risk of recurrent seizures (42, 43)
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In the STEP-1 trial, DEXA scans showed that lean body mass (muscle and bone) accounted for nearly 40 percent of the weight lost
It should be noted that GIPR antagonism paradoxically produces additive weight loss when paired to GLP-1R agonism in preclinical studies (5860) and that this mechanism appears relevant in patients with obesity (61)
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