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However, a multicenter study in 5,485 subjects with cardiovascular disease or diabetes mellitus showed that daily supplementation with folic acid (2.5 mg), vitamin B 12 (1 mg), and vitamin B6 (50 mg) lowered homocysteine concentrations but had no effect on fracture risk compared to placebo (118)
group 3 was diabetic treated orally with 250mg/kg magnesium (DMg250) while group 4 was diabetic treated subcutaneously with 3 IU/kg insulin (DI) for 21 days respectively
Most users report initial energy improvements within 35 days to 2 weeks if baseline B12 was deficient
J Neurochem , 75:14381446
Braz J Med Biol Res
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