soul trial oral semaglutide cardiovascular outcomes 2024 results nejm and in Patients with Type 2 Diabetes Cardiovascular outcomes of semaglutide and

Slower gut motility is part of the therapeutic effect, helping with appetite control and blood sugar regulation

16 However, the burden of gastrointestinal side effects and challenges with long-term adherence limited its broader applicability and underscored the need for more effective and better-tolerated therapeutic alternatives

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1 Flow chart of the review process

Digestive/GI side effects are common: nausea, vomiting, diarrhea, constipation, delayed gastric emptying (gastroparesis) have all been documented