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La farmacocintica de semaglutida se evalu en pacientes con diversos grados de insuficiencia heptica (leve, moderada, grave) comparados con sujetos con funcin heptica normal en un estudio en el que se utiliz dosis nica de 0.5 mg de semaglutida

Mounjaro is approved for adults and children 10 years and over with type 2 diabetes

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It differs from the native 70 residue growth factor in two respects: glutamate at position 3 is replaced by arginine, and a hydrophobic 13 residue extension (MFPAMPLLSLFVN) is fused to the N-terminus