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Xu, G., Zhou, T., Gu, Y., Wang, Q., Shariff, M., Gu, P., Nguyen, T., Shi, R., & Rao, J

Potential side effects for this group include those that would also affect teenagers, such as nausea, vomiting, and pancreatitis

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Pillar 6: Pioglitazone (PPAR-gamma agonist) Pioglitazone can improve insulin sensitivity partly by redistributing fat away from ectopic depots (liver and muscle) towards safer subcutaneous stores

Multiple pathways of NAD + synthesis have been identified, which are differentially active in tissues and utilize various molecular precursors to ensure maintenance of NAD + homeostasis and counteract NAD + turnover