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doi:10.1080/07315724.2019.1661804

Pola P, Savi M, Grilli M, and et al

In the recently published BARI-OPTIMISE double-blind, placebo-controlled trial, 70 patients post-SG or RYGB who were tested and found to have insufficient GLP-1 response to meal stimulation were randomized to receive liraglutide (3 mg/day) or placebo, in addition to lifestyle interventions [49]

When water intake drops while the medication simultaneously slows digestion and allows more water absorption from stool, constipation becomes almost inevitable without conscious effort to stay hydrated

This has the additional advantage of reducing body weight by reducing percentage fat in the body