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For patients at Dwarika Gastro, emphasize monitoring post-stop.[user context][9] Sources [1] Over Half Regain Weight After Stopping GLP-1s [2] Metabolic rebound after GLP-1 receptor agonist discontinuation [3] Semaglutide Treatment Effect in People With Obesity STEP 1 [4] Weight regain and cardiometabolic effects after withdrawal of PMC [5] Weight Loss and Maintenance Related to the Mechanism of Action [6] Weight Reduction with GLP-1 Agonists and Paths for PMC [7] Metabolic rebound after GLP-1 receptor agonist [8] The SURMOUNT-4 Randomized Clinical Trial PubMed [9] Study Reveals Weight Regain Post GLP-1 Receptor Agonist Treatment [10] Why Weight Regain Happens After GLP-1s [11] REBOUND OBESITY AFTER GLP-1 AGONISTS DISCONTINUATION [12] A Comprehensive Review on Weight Gain following PMC [13] A Post Hoc Analysis of the SURMOUNT-4 Trial PubMed [14] Weight Regain After Liraglutide, Semaglutide or Tirzepatide [15] Weight Maintenance after GLP-1 RA Withdrawal Exposes Critical [16] Post metabolic bariatric surgery weight regain: the importance of GLP-1 levels [17] Rebound or Retention: A Meta-Analysis of Weight Regain After the [18] Semaglutide Treatment Effect in People With Obesity STEP 1 [19] Time to weight plateau with tirzepatide treatment in the PMC Be the first to share your thoughts on this article.

Because of these risks, tirzepatide must be kept at refrigerator temperature (between 36F and 46F, or 2C to 8C)

Clinical trials have shown that semaglutide is highly effective, with individuals achieving a weight loss of 15-20% of their body weight